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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1A
All Species:
10.61
Human Site:
S1353
Identified Species:
19.44
UniProt:
O95602
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95602
NP_056240.2
1720
194811
S1353
F
F
K
L
L
M
E
S
I
K
K
K
N
N
K
Chimpanzee
Pan troglodytes
XP_001135380
1723
195055
S1353
F
F
K
L
L
M
E
S
I
K
K
K
N
N
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532976
1699
192037
S1335
F
F
K
I
L
M
E
S
L
R
K
K
N
N
K
Cat
Felis silvestris
Mouse
Mus musculus
O35134
1717
194092
A1360
F
F
K
L
L
M
E
A
I
K
K
K
K
N
K
Rat
Rattus norvegicus
O54889
1716
194174
A1360
F
F
K
L
L
M
E
A
I
K
K
K
N
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL98
1390
155685
R1069
N
I
T
L
G
V
P
R
I
K
E
I
I
N
A
Frog
Xenopus laevis
NP_001082182
1730
195193
A1358
F
F
K
I
M
F
D
A
I
K
R
K
S
S
K
Zebra Danio
Brachydanio rerio
XP_001922839
1693
190636
A1347
F
F
R
M
L
L
E
A
I
K
K
L
T
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91875
1642
185391
I1317
F
K
Q
L
I
R
A
I
L
K
V
S
N
A
S
Honey Bee
Apis mellifera
XP_001121092
1665
190473
E1302
F
F
K
E
I
F
K
E
I
K
K
V
A
K
I
Nematode Worm
Caenorhab. elegans
NP_001022450
1737
195064
T1385
K
K
K
Y
H
E
I
T
D
Y
Q
Q
M
S
H
Sea Urchin
Strong. purpuratus
XP_794863
1742
194988
I1354
F
L
K
Q
F
L
E
I
V
K
R
K
M
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10964
1664
186413
Q1336
I
V
K
E
I
K
K
Q
K
R
T
T
G
P
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
90
N.A.
86.8
87.9
N.A.
N.A.
27
68.1
67.9
N.A.
43.7
43.6
39.3
46.8
Protein Similarity:
100
99.1
N.A.
94.4
N.A.
93.3
93.8
N.A.
N.A.
43.9
81.7
81.3
N.A.
61.4
61.5
57.4
64.4
P-Site Identity:
100
100
N.A.
80
N.A.
86.6
86.6
N.A.
N.A.
26.6
46.6
53.3
N.A.
26.6
40
6.6
33.3
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
N.A.
40
93.3
80
N.A.
46.6
53.3
33.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
31
0
0
0
0
8
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
16
% D
% Glu:
0
0
0
16
0
8
54
8
0
0
8
0
0
0
0
% E
% Phe:
77
62
0
0
8
16
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
8
0
16
24
0
8
16
62
0
0
8
8
0
8
% I
% Lys:
8
16
77
0
0
8
16
0
8
77
54
54
8
16
54
% K
% Leu:
0
8
0
47
47
16
0
0
16
0
0
8
0
0
0
% L
% Met:
0
0
0
8
8
39
0
0
0
0
0
0
16
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
39
39
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
8
8
0
0
0
8
0
0
8
8
0
0
0
% Q
% Arg:
0
0
8
0
0
8
0
8
0
16
16
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
24
0
0
0
8
8
24
8
% S
% Thr:
0
0
8
0
0
0
0
8
0
0
8
8
8
0
0
% T
% Val:
0
8
0
0
0
8
0
0
8
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _